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Talk:Trifluoroacetate counterion

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This is the discussion page for the article Trifluoroacetate counterion. It is for improving the article: sources, wording, structure, scope and titles. It is not a general discussion forum about the subject, and it is not a place to ask for advice — see Project:Medical disclaimer.

The worked arithmeticResolved

99% pure, 15% counterion, 6% water, therefore about 78% peptide. That single line does more work than the rest of the article. TFA_Counterion (talk) 09:35, 5 March 2026 (UTC)

Agreed, and it is arithmetic a reader can check, which is what makes it persuasive rather than merely assertive. ✓ Done PlainNumbersPip (talk) 13:10, 5 March 2026 (UTC)

Resolved. This thread is closed. Reopening it is fine if new sources appear; please add a new subsection rather than editing the closed discussion.

Assay interference claim

The claim about interference with cell-based assays is sourced to a methods paper on counterion exchange rather than to a study of interference. Should it be softened? PrimarySrcPatia (talk) 10:15, 28 May 2026 (UTC)

It is phrased as "reported to interfere", which is a claim about the literature rather than about the world. I would leave it and welcome a better source. Peptide_Pete (talk) 13:45, 28 May 2026 (UTC)

Range of counterion contentDone

5 to 25% is a wide range. Is it worth explaining that the figure tracks the number of basic residues? SigFigSindri (talk) 11:05, 26 June 2026 (UTC)

The lead already says it is sequence-dependent and names the residues. That is the explanation without pretending to a precision the figures do not have. ✓ Done MolarMassMaeve (talk) 14:30, 26 June 2026 (UTC)

Done. This thread is closed. Reopening it is fine if new sources appear; please add a new subsection rather than editing the closed discussion.
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