Project:Analytical working group

Coordinating chromatography, spectrometry and compendial testing articles.

The analytical working group covers separation science, mass spectrometry, the compendial tests and method validation, and it owns the wiki's treatment of what a purity figure does and does not mean.

Chromatography, mass spectrometry, water determination, endotoxin and sterility testing, impurities and counterions, reference standards, and analytical method validation. The certificate-of-analysis articles are shared with the quality group.

The group's recurring work is correcting the conflation of area percent purity with peptide content — in articles, in talk-page arguments and in the sources the wiki cites. Any article that quotes a purity figure should make clear what the figure is relative to, and any article that quotes a mass should make clear whether it is gross or net.

1. Individually source the interference claims in the water-determination articles.
2. Add a worked limit-of-detection calculation using real signal-to-noise figures.
3. Document each independent testing service's sampling and reporting practice in its own article, rather than only by comparison with the others.
4. Standardise chromatographic parameter reporting: column, mobile phase, gradient, detection wavelength, in that order.