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Talk:Glucagon

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This article is within the scope of the pharmacology working group.

This is the discussion page for the article Glucagon. It is for improving the article: sources, wording, structure, scope and titles. It is not a general discussion forum about the subject, and it is not a place to ask for advice — see Project:Medical disclaimer.

Energy-expenditure figure

"3–8%" for resting energy expenditure is doing a lot of work and is sourced to early-phase studies with small numbers. Can we say how it was measured? Indirect calorimetry over what period? PlainNumbersPip (talk) 10:40, 6 May 2026 (UTC)

The published figures come from short indirect-calorimetry sessions, and the article now says "figures in the region of" rather than stating a range as established. I agree it is weak evidence and the wording should stay hedged. MolarMassMaeve (talk) 14:15, 6 May 2026 (UTC)

Fibrillation paragraph belongs here or at aggregation?Resolved

The formulation section drifts into general advice about reconstituted solutions. That is Peptide aggregation and Reconstitution of lyophilised peptides territory. StabilityStig (talk) 08:25, 12 March 2026 (UTC)

Trimmed to one sentence of general application with links out, keeping the glucagon-specific history. Glucagon is the clearest worked example of the problem so a short generalisation earns its place. ✓ Done LyophilLena (talk) 11:50, 12 March 2026 (UTC)

Resolved. This thread is closed. Reopening it is fine if new sources appear; please add a new subsection rather than editing the closed discussion.

GIP and glucagon secretion — contradiction with the GIP article?Done

This article says GIP stimulates glucagon secretion at euglycaemia. Glucose-dependent insulinotropic polypeptide does not mention it. One of the two should be brought into line. GIP_Genoveva (talk) 09:33, 9 January 2026 (UTC)

Both are correct as far as they go; the GIP article simply does not cover alpha-cell effects. I have flagged it there rather than removing anything here. IncretinIvo (talk) 12:47, 9 January 2026 (UTC)

Agreed, that is the better fix. ✓ Done GIP_Genoveva (talk) 08:12, 10 January 2026 (UTC)

Done. This thread is closed. Reopening it is fine if new sources appear; please add a new subsection rather than editing the closed discussion.
This page was last edited on 6 May 2026, by MolarMassMaeve. Text is available under the PeptidePedia Wiki Content Licence (PPCL-BY-SA 4.0).