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Talk:Dual incretin agonist

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This article is within the scope of the pharmacology working group.

This is the discussion page for the article Dual incretin agonist. It is for improving the article: sources, wording, structure, scope and titles. It is not a general discussion forum about the subject, and it is not a place to ask for advice — see Project:Medical disclaimer.

The GIP agonist-versus-antagonist problem

The article notes that GIP-receptor antagonists have also produced weight loss. That is the single most awkward fact in this field and I am glad it is stated rather than glossed. Should it be expanded? GIP_Genoveva (talk) 09:20, 3 April 2026 (UTC)

It is worth a sentence explaining the reconciliation that is usually offered — that sustained agonism produces functional antagonism through desensitisation — but stating it as the answer would overreach. IncretinIvo (talk) 13:45, 3 April 2026 (UTC)

Agreed. The word "disputed" is carrying the right weight as it stands. GIP_Genoveva (talk) 08:55, 4 April 2026 (UTC)

Numbered list in the middle sectionResolved

Three competing explanations as a numbered list reads as a ranking. They are not ranked. Suggest either unnumbered or an explicit statement that the order carries no weight. ManualOfStyleMo (talk) 10:40, 25 February 2026 (UTC)

Added a closing sentence saying none has been isolated experimentally, which removes the ranking implication without losing the list structure. ✓ Done Hedgerow_Hal (talk) 14:12, 25 February 2026 (UTC)

Resolved. This thread is closed. Reopening it is fine if new sources appear; please add a new subsection rather than editing the closed discussion.

Is "twincretin" acceptable in an encyclopedia?Done

The infobox lists "twincretin" as an alternative name. It is journalistic rather than technical. Keep or drop? GlossaryGleb (talk) 11:30, 19 January 2026 (UTC)

Keep. Readers encounter it and need to know it means this. Listing a term is not endorsing it as house style. ✓ Done DefinedTermDov (talk) 15:05, 19 January 2026 (UTC)

Done. This thread is closed. Reopening it is fine if new sources appear; please add a new subsection rather than editing the closed discussion.
This page was last edited on 4 April 2026, by GIP_Genoveva. Text is available under the PeptidePedia Wiki Content Licence (PPCL-BY-SA 4.0).