Subcutaneous injection: difference between revisions
Diff·revision 20 → 21·01:03, 17 May 2025
Difference between revision 20 and revision 21 of Subcutaneous injection. 5 lines changed; the page grew by 559 bytes.
| Revision 20 — 01:32, 24 Apr 2025 StubTagTeodor (talk) state that swirling rather than shaking is the handling convention, sourced 4,081 bytes +42 | Revision 21 — 01:03, 17 May 2025 BPC_Bramwell (talk) state the assumption that the whole vial is reconstituted at once 4,640 bytes +559 | ||
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| 34 | Local blood flow modifies all of these. Heat, exercise and massage increase it; cold reduces it. These effects are largest for preparations whose absorption is fast to begin with.{{r|ada2024}} | 34 | Local blood flow modifies all of these. Heat, exercise and massage increase it; cold reduces it. These effects are largest for preparations whose absorption is fast to begin with.{{r|ada2024}} |
| 35 | 35 | ||
| + | 36 | == Local reactions and rotation == | |
| + | 37 | Repeated injection at one site produces local changes — lipohypertrophy, in which the subcutaneous tissue thickens, and less commonly lipoatrophy. Absorption from affected tissue is erratic and generally reduced, which makes the resulting exposure unpredictable.{{r|ada2024}} | |
| + | 38 | ||
| + | 39 | [[Injection site rotation|Rotation]] between and within sites is the established response. Rotation within a region preserves the region's absorption characteristics while spreading the mechanical insult; rotation between regions changes both. | |
| + | 40 | ||
| 36 | == References == | 41 | == References == |
| 37 | {{reflist}} | 42 | {{reflist}} |