Reconstitution calculator (revision 4)
Old revision·14:06, 10 Sep 2024·CoI_Corin
| Reconstitution calculator | |
|---|---|
| Inputs | Vial mass (mg), diluent volume (mL), dose (mg or µg), syringe scale |
| Outputs | Concentration, dose volume, syringe units, doses per vial |
| Reference tool infobox · conventions | |
The reconstitution calculator relates the four quantities involved in dissolving a lyophilised peptide and drawing a dose from it: the mass of solid in the vial, the volume of diluent added, the intended dose, and the reading on the syringe barrel. All four are connected by one division, and almost every error reported in the literature and in community accounts is a confusion between two of them rather than a failure of the arithmetic itself.[1]
The calculation is a routine unit conversion: concentration is mass divided by volume, dose volume is dose divided by concentration, and a syringe unit is one hundredth of a millilitre on the U-100 scale. The tool below performs those operations and shows each intermediate result, because the intermediate is where a mistake becomes visible.
References
- ^ United States Pharmacopeia, General Chapter <797>, "Pharmaceutical Compounding — Sterile Preparations". USP–NF, current revision.