Reconstitution calculator: difference between revisions
Diff·revision 41 → 42·03:43, 26 Jul 2025
Difference between revision 41 and revision 42 of Reconstitution calculator. 8 lines changed; the page grew by 728 bytes.
| Revision 41 — 05:01, 14 Jul 2025 NeutralNikolai (talk) rv promotional edit 7,641 bytes +158 | Revision 42 — 03:43, 26 Jul 2025 DeletionDeb (talk) rv restoration of unsourced claim 8,369 bytes +728 | ||
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| 67 | {{figure|syringe|Graduations on a 1 mL U-100 barrel. The scale reads volume; the mass it corresponds to depends entirely on the concentration in the vial.}} | 67 | {{figure|syringe|Graduations on a 1 mL U-100 barrel. The scale reads volume; the mass it corresponds to depends entirely on the concentration in the vial.}} |
| 68 | 68 | ||
| + | 69 | == Limitations == | |
| + | 70 | The tool assumes complete dissolution, an accurate label mass, an accurately measured diluent volume, and a syringe manufactured to its nominal scale. Each of those is an approximation: | |
| + | 71 | ||
| + | 72 | * incomplete dissolution leaves a concentration lower than calculated and a suspension of unknown uniformity; | |
| + | 73 | * diluent volume drawn on the same syringe used for dosing carries that syringe's own error; | |
| + | 74 | * syringe volume tolerance under ISO 7886 is a few percent of nominal capacity, which at the bottom of the barrel is a large fraction of a small dose;{{r|iso7886}} | |
| + | 75 | * [[Peptide aggregation|aggregated]] or partly degraded material has a peptide content lower than the certificate reports, and no arithmetic detects that. | |
| + | 76 | ||
| 69 | == References == | 77 | == References == |
| 70 | {{reflist}} | 78 | {{reflist}} |