Peptide stability table: difference between revisions
Diff·revision 34 → 35·06:38, 16 Jun 2025
Difference between revision 34 and revision 35 of Peptide stability table. 2 lines changed; the page grew by 231 bytes.
| Revision 34 — 10:32, 9 Jun 2025 ConsensusConal (talk) move table to the section it supports 4,891 bytes ±0 | Revision 35 — 06:38, 16 Jun 2025 NotabilityNoa (talk) remove weasel wording 5,122 bytes +231 | ||
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| 38 | '''The assay differs.''' A stability-indicating [[High-performance liquid chromatography|HPLC]] method that resolves the principal degradant reports loss that a method which co-elutes it does not. [[Analytical method validation|Method validation]] is what establishes that a method is stability-indicating, and research-compound figures rarely state whether it was.{{r|ich}} | 38 | '''The assay differs.''' A stability-indicating [[High-performance liquid chromatography|HPLC]] method that resolves the principal degradant reports loss that a method which co-elutes it does not. [[Analytical method validation|Method validation]] is what establishes that a method is stability-indicating, and research-compound figures rarely state whether it was.{{r|ich}} |
| 39 | 39 | ||
| + | 40 | '''The container differs.''' Adsorption to glass, extractables from a stopper, and headspace oxygen all affect degradation rate. A figure obtained in a Type I glass vial with a coated stopper does not transfer to an uncoated one. | |
| + | 41 | ||
| 40 | == References == | 42 | == References == |
| 41 | {{reflist}} | 43 | {{reflist}} |