Haemoglobin A1c (revision 1)
Old revision·09:00, 26 Jul 2024·MissedDoseMik
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| Haemoglobin A1c | |
|---|---|
| Abbreviation | HbA1c |
| Reflects | Average glucose over ~8–12 weeks |
| Units | mmol/mol (IFCC); % (DCCT/NGSP) |
| Confounded by | Anything altering red-cell lifespan |
| Topic infobox · conventions | |
Haemoglobin A1c is the fraction of haemoglobin that has been non-enzymatically glycated. Because glycation is irreversible and proceeds at a rate proportional to glucose concentration, the fraction integrates glucose exposure over the lifespan of the circulating red cells — roughly the preceding eight to twelve weeks, weighted towards the more recent.[1]
It is reported in two unit systems: mmol/mol under the IFCC reference method, and percentage under the older DCCT-aligned convention. Both appear in the literature and conversion between them is defined.[2]
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