Haemoglobin A1c: difference between revisions
Diff·revision 1 → 2·06:56, 31 Jul 2024
Difference between revision 1 and revision 2 of Haemoglobin A1c. 5 lines changed; the page grew by 548 bytes.
| Revision 1 — 09:00, 26 Jul 2024 MissedDoseMik (talk) create article — laboratory stub 1,274 bytes +1,274 | Revision 2 — 06:56, 31 Jul 2024 FerritinFay (talk) serial comma per PP:MOS 1,822 bytes +548 | ||
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| 11 | It is reported in two unit systems: mmol/mol under the IFCC reference method, and percentage under the older DCCT-aligned convention. Both appear in the literature and conversion between them is defined.{{r|nathan2008}} | 11 | It is reported in two unit systems: mmol/mol under the IFCC reference method, and percentage under the older DCCT-aligned convention. Both appear in the literature and conversion between them is defined.{{r|nathan2008}} |
| 12 | 12 | ||
| + | 13 | == What it measures == | |
| + | 14 | Glycation is a slow non-enzymatic reaction between glucose and the N-terminal valine of the haemoglobin β-chain. Its extent depends on both glucose concentration and exposure time, and because red cells are replaced continuously the population of cells sampled at any moment carries a weighted history.{{r|nathan2008}} | |
| + | 15 | ||
| + | 16 | The weighting is not uniform: roughly half the value reflects the preceding month, and the remainder the two months before. A change made three weeks ago is therefore only partly expressed.{{r|ada2024}} | |
| + | 17 | ||
| 13 | == References == | 18 | == References == |
| 14 | {{reflist}} | 19 | {{reflist}} |