GLP-1 receptor: difference between revisions
Diff·revision 20 → 21·13:15, 11 May 2025
Difference between revision 20 and revision 21 of GLP-1 receptor. 2 lines changed; the page grew by 252 bytes.
| Revision 20 — 13:28, 21 Apr 2025 Retention_Time_Rae (talk) clarify that the receptor is expressed outside the pancreas 6,418 bytes ±0 | Revision 21 — 13:15, 11 May 2025 ExenatideEzra (talk) convert a hard-coded date to the house format 6,670 bytes +252 | ||
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| 51 | The area postrema lies outside the blood-brain barrier, which is why a peptide too large to cross it can nonetheless produce centrally mediated nausea. Access to the arcuate nucleus is partly via fenestrated capillaries at the median eminence and partly via vagal afferents.{{r|graaf2016}} | 51 | The area postrema lies outside the blood-brain barrier, which is why a peptide too large to cross it can nonetheless produce centrally mediated nausea. Access to the arcuate nucleus is partly via fenestrated capillaries at the median eminence and partly via vagal afferents.{{r|graaf2016}} |
| 52 | 52 | ||
| + | 53 | The modest resting heart-rate increase of two to four beats per minute reported across the class is attributed to direct action at the sinoatrial node. It has not been associated with adverse outcomes in the completed outcome trials.{{r|drucker2018}} | |
| + | 54 | ||
| 53 | == References == | 55 | == References == |
| 54 | {{reflist}} | 56 | {{reflist}} |