GLP-1 receptor: difference between revisions
Diff·revision 11 → 12·12:02, 6 Nov 2024
Difference between revision 11 and revision 12 of GLP-1 receptor. 5 lines changed; the page grew by 204 bytes.
| Revision 11 — 08:53, 22 Oct 2024 HalfLifeHavel (talk) alphabetise the see-also list 4,864 bytes ±0 | Revision 12 — 12:02, 6 Nov 2024 DPP4_Dagmar (talk) the numbers in the lead disagreed with the body; body was right 5,068 bytes +204 | ||
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| 1 | {{Infobox concept | 1 | {{Infobox concept |
| 2 | | name = GLP-1 receptor | 2 | | name = GLP-1 receptor |
| + | 3 | | subtitle = Class B GPCR | |
| 3 | | image = receptor.svg | 4 | | image = receptor.svg |
| 4 | | caption = Extracellular domain capture followed by insertion of the peptide N-terminus into the transmembrane bundle. | 5 | | caption = Extracellular domain capture followed by insertion of the peptide N-terminus into the transmembrane bundle. |
| ⋮ | ⋮ | ||
| 10 | | Secondary = G<sub>q</sub>, β-arrestin recruitment | 11 | | Secondary = G<sub>q</sub>, β-arrestin recruitment |
| 11 | | Desensitisation = GRK phosphorylation, internalisation | 12 | | Desensitisation = GRK phosphorylation, internalisation |
| + | 13 | <!-- Expression --> | |
| + | 14 | | Pancreas = Beta cells, some alpha and delta cells | |
| + | 15 | | Central = Area postrema, hypothalamus, brainstem | |
| + | 16 | | Peripheral = Stomach, heart, kidney, lung | |
| 12 | }} | 17 | }} |
| 13 | 18 |