Cold chain: difference between revisions
Diff·revision 63 → 64·15:28, 2 Aug 2025
Difference between revision 63 and revision 64 of Cold chain. 9 lines changed; the page grew by 528 bytes.
| Revision 63 — 23:19, 24 Jul 2025 RotationRosalind (talk) rm citation to a supplier's own page 23,501 bytes +506 | Revision 64 — 15:28, 2 Aug 2025 RepackRadek (talk) correct percentage: source reports placebo-adjusted 24,029 bytes +528 | ||
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| 136 | '''Documentation failure.''' A shipment may be correctly maintained and still be unusable in a regulated setting if the record is missing, unreadable or not attributable. Distribution guidance treats the record as part of the product's quality status, not as administrative overhead.{{r|eugdp2013}} | 136 | '''Documentation failure.''' A shipment may be correctly maintained and still be unusable in a regulated setting if the record is missing, unreadable or not attributable. Distribution guidance treats the record as part of the product's quality status, not as administrative overhead.{{r|eugdp2013}} |
| 137 | 137 | ||
| + | 138 | | Failure point | Characteristic mechanism | Detected by | | |
| + | 139 | |---|---|---| | |
| + | 140 | | Packing | Direct coolant contact; part-full payload | Payload logger | | |
| + | 141 | | Air freight | Extended hold at ramp temperature | Shipment logger | | |
| + | 142 | | Customs | Hold of unpredictable duration | Logger, if retrieved | | |
| + | 143 | | Courier depot | Unrefrigerated overnight storage | Shipment logger | | |
| + | 144 | | Doorstep delivery | Local ambient until collection | Nothing, in general | | |
| + | 145 | | Domestic refrigerator | Compartment gradient; door-shelf placement | Min–max thermometer | | |
| + | 146 | ||
| 138 | == Distribution outside regulated channels == | 147 | == Distribution outside regulated channels == |
| 139 | A substantial proportion of the material discussed on this wiki moves outside pharmaceutical distribution, and the cold-chain concept applies to it only partially. The differences are structural rather than incidental. | 148 | A substantial proportion of the material discussed on this wiki moves outside pharmaceutical distribution, and the cold-chain concept applies to it only partially. The differences are structural rather than incidental. |