Beyond-use date: difference between revisions
Diff·revision 57 → 58·03:01, 6 Nov 2025
Difference between revision 57 and revision 58 of Beyond-use date. 4 lines changed; the page grew by 974 bytes.
| Revision 57 — 02:58, 30 Oct 2025 FreightFenna (talk) add PMID 21,165 bytes ±0 | Revision 58 — 03:01, 6 Nov 2025 LyophilLena (talk) expand §Assignment in the absence of data 22,139 bytes +974 | ||
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| 128 | For an opened manufactured container the equivalent record is the date of first entry, annotated on the container. Guidance treats an unannotated multiple-dose container as undatable and therefore to be discarded, on the ground that no evidence exists that it is within its period.{{r|usp797,cdc_injection_bud}} | 128 | For an opened manufactured container the equivalent record is the date of first entry, annotated on the container. Guidance treats an unannotated multiple-dose container as undatable and therefore to be discarded, on the ground that no evidence exists that it is within its period.{{r|usp797,cdc_injection_bud}} |
| 129 | 129 | ||
| + | 130 | For reconstituted research peptides the recording problem is compounded by the labelling problem discussed at [[Vial|vial]]: a vial that carries no manufacturer label offers nowhere obvious to write, and a vial whose contents are identified only by a discarded outer package cannot be annotated meaningfully at all. Community practice of marking the closure or the ferrule with the reconstitution date is the common workaround and is recorded here as practice rather than recommended.{{r|ppbud}} | |
| + | 131 | ||
| 130 | == Terminology and the conflation problem == | 132 | == Terminology and the conflation problem == |
| 131 | The two kinds of date are conflated pervasively, and the conflation is not merely pedantic to correct, because the two respond differently to the questions readers ask. | 133 | The two kinds of date are conflated pervasively, and the conflation is not merely pedantic to correct, because the two respond differently to the questions readers ask. |
| ⋮ | ⋮ | ||
| 136 | 138 | ||
| 137 | Asked whether refrigeration helps, the answers differ, as set out in §Definition and contrast with the expiration date. | 139 | Asked whether refrigeration helps, the answers differ, as set out in §Definition and contrast with the expiration date. |
| + | 140 | ||
| + | 141 | The convention adopted on this wiki after a 2026 request for comment is that ''expiration date'' is used only for manufacturer dating supported by a stability programme; ''beyond-use date'' for dating assigned by a compounder, dispenser or user; and ''in-use period'' for a manufacturer-specified period after first use or reconstitution, which is a third thing again — it is manufacturer dating, supported by stability data, but applying to an opened container.{{r|ppbud}} | |
| 138 | 142 | ||
| 139 | == References == | 143 | == References == |