Underfilling (revision 2)
Old revision·04:08, 19 Nov 2024·Chromatokid
This is an old revision of this page, as it stood at 04:08, 19 Nov 2024, saved by Chromatokid with the summary add the note that a purity figure without water and counterion is not a mass. It may differ substantially from the current revision, and any error it contains may since have been corrected.
| Underfilling | |
|---|---|
| Failure | Delivered mass below nominal |
| Not detected by | Purity determination |
| Detected by | Gravimetric fill check, or content with fill mass |
| Topic infobox · conventions | |
Underfilling is the delivery of less material in a container than the quantity stated on its label. It is a distinct failure from impurity and is invisible to the determination most often supplied: area percent purity is normalised and does not change with the amount of material present.[1]
The quantity a purchaser cares about is the mass of peptide in the vial. That is the product of three things — the fill mass, the peptide content of the solid, and the purity — and a certificate reporting only the last of these constrains it hardly at all.[1]
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