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Trial data comparison: difference between revisions

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Revision 45 — 20:21, 1 Sep 2025
PuffRemoverPax (talk)
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Revision 46 — 10:29, 10 Sep 2025
INN_Ingrid (talk)
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56'''Comparator.''' Placebo-controlled and active-controlled trials answer different questions. A placebo-adjusted difference and an absolute change are frequently confused; see [[Placebo-adjusted effect]].56'''Comparator.''' Placebo-controlled and active-controlled trials answer different questions. A placebo-adjusted difference and an absolute change are frequently confused; see [[Placebo-adjusted effect]].
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+58== Outcome trials are a different kind of evidence ==
+59{{seealso|SELECT trial|FLOW trial|LEADER trial}}
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+61Three of the rows report hazard ratios for clinical events rather than changes in a measurement. These are the strongest evidence in the table and the least comparable to the rest of it: an event-driven trial reports a relative risk over years in a population selected for risk, and a hazard ratio cannot be placed alongside a percentage weight change in any meaningful ordering.
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58== References ==63== References ==
59{{reflist}}64{{reflist}}