Syringe dead space: difference between revisions
Diff·revision 24 → 25·16:58, 17 Nov 2025
Difference between revision 24 and revision 25 of Syringe dead space. 4 lines changed; the page grew by 548 bytes.
| Revision 24 — 04:40, 14 Nov 2025 TitrationTheo (talk) de-orphan 10,608 bytes +182 | Revision 25 — 16:58, 17 Nov 2025 ArchiveBot (talk) bot: flag bare reference 11,156 bytes +548 | ||
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| 87 | A worked case. A vial containing 5.0 mg of peptide is reconstituted with 2.00 mL of diluent, giving 2.50 mg·mL⁻¹. An intended dose of 0.50 mg corresponds to 0.20 mL. | 87 | A worked case. A vial containing 5.0 mg of peptide is reconstituted with 2.00 mL of diluent, giving 2.50 mg·mL⁻¹. An intended dose of 0.50 mg corresponds to 0.20 mL. |
| 88 | 88 | ||
| + | 89 | * With a device of 0.070 mL dead space and an unexpelled hub air pocket of that size, the liquid delivered is 0.20 − 0.07 = 0.13 mL, containing 0.325 mg. The shortfall is 35% of the intended dose. | |
| + | 90 | * With the same device correctly primed and free of air, 0.20 mL and 0.50 mg are delivered, and 0.070 mL — 0.175 mg — is discarded in the device. | |
| + | 91 | * For a smaller intended dose of 0.05 mL, the same 0.070 mL dead space exceeds the dose entirely; no plunger position can deliver 0.05 mL if that volume of air must first be displaced from the hub. | |
| + | 92 | ||
| 89 | == References == | 93 | == References == |
| 90 | {{reflist}} | 94 | {{reflist}} |