Sarcopenia: difference between revisions
Diff·revision 9 → 10·09:30, 8 Mar 2025
Difference between revision 9 and revision 10 of Sarcopenia. 6 lines changed; the page grew by 581 bytes.
| Revision 9 — 04:25, 24 Feb 2025 B12_Bettina (talk) split the analytical performance from the clinical interpretation 2,738 bytes ±0 | Revision 10 — 09:30, 8 Mar 2025 AnalyticalAnnie (talk) state the assay the reference interval was established on 3,319 bytes +581 | ||
|---|---|---|---|
| 1 | {{Infobox concept | 1 | {{Infobox concept |
| 2 | | name = Sarcopenia | 2 | | name = Sarcopenia |
| + | 3 | | subtitle = Clinical practice | |
| 3 | | Defined by = Low muscle strength, confirmed by low muscle quantity | 4 | | Defined by = Low muscle strength, confirmed by low muscle quantity |
| 4 | | Assessed by = Grip strength, chair-stand time, gait speed | 5 | | Assessed by = Grip strength, chair-stand time, gait speed |
| ⋮ | ⋮ | ||
| 24 | 25 | ||
| 25 | Sarcopenic obesity — low muscle with high fat mass — is a recognised phenotype and is harder to detect, since body weight does not signal it and the muscle deficit is concealed by adiposity.{{r|heymsfield2015}} | 26 | Sarcopenic obesity — low muscle with high fat mass — is a recognised phenotype and is harder to detect, since body weight does not signal it and the muscle deficit is concealed by adiposity.{{r|heymsfield2015}} |
| + | 27 | ||
| + | 28 | == Relevance to weight reduction == | |
| + | 29 | All substantial weight loss reduces lean mass to some degree, and the compartment includes organ and water components as well as muscle. See [[Body composition assessment]].{{r|heymsfield2015}} | |
| + | 30 | ||
| + | 31 | The specific question — whether pharmacological weight loss reduces muscle disproportionately compared with equivalent loss by other means — is not answered by existing trials, which measured composition in subsets as a secondary outcome and compared against placebo arms losing little weight.{{r|wilding2021}} | |
| 26 | 32 | ||
| 27 | == References == | 33 | == References == |