Placebo-adjusted effect: difference between revisions
Diff·revision 17 → 18·00:57, 12 Sep 2025
Difference between revision 17 and revision 18 of Placebo-adjusted effect. 2 lines changed; the page grew by 224 bytes.
| Revision 17 — 14:36, 15 Aug 2025 ITT_Imelda (talk) add the discontinuation rate for adverse events in both arms 4,581 bytes ±0 | Revision 18 — 00:57, 12 Sep 2025 SurmountSurma (talk) add the year of publication to each trial in the list 4,805 bytes +224 | ||
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| 37 | Nor does it address blinding failure. An agent producing marked gastrointestinal effects is not perfectly blinded in practice, and participants who infer their allocation may behave differently. This is unquantifiable and is a general limitation of trials of agents with distinctive effects.{{r|hrobjartsson2010}} | 37 | Nor does it address blinding failure. An agent producing marked gastrointestinal effects is not perfectly blinded in practice, and participants who infer their allocation may behave differently. This is unquantifiable and is a general limitation of trials of agents with distinctive effects.{{r|hrobjartsson2010}} |
| 38 | 38 | ||
| + | 39 | For a reader, the practical discipline is to ask three questions of any quoted figure: is it placebo-adjusted, over what duration, and in what population. A figure lacking any of the three is not interpretable.{{r|ich_e9}} | |
| + | 40 | ||
| 39 | == References == | 41 | == References == |
| 40 | {{reflist}} | 42 | {{reflist}} |