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Patent expiry and biosimilars: difference between revisions

Diff·revision 15 → 16·12:11, 25 Jul 2025

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Revision 15 — 16:41, 8 Jul 2025
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Revision 16 — 12:11, 25 Jul 2025
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27The consequence is that a peptide generic is a more analytically demanding application than a small-molecule generic, and the analytical package rather than the clinical one carries the argument.{{r|fda_peptide}}27The consequence is that a peptide generic is a more analytically demanding application than a small-molecule generic, and the analytical package rather than the clinical one carries the argument.{{r|fda_peptide}}
2828
+29== Consequences for supply ==
+30Patent expiry changes the commercial landscape rather than the chemistry. A molecule whose protection has lapsed can be made and sold lawfully by anyone able to meet the regulatory requirements, and prices fall accordingly. See [[Cost per milligram]].{{r|ema_biosimilar}}
+31
+32It does not change the status of research-chemical supply, which is a separate category question: material sold as a reagent is not a medicine regardless of whether the reference product is still protected. See [[Regulatory status by jurisdiction]].{{r|usp1503}}
+33
29== References ==34== References ==
30{{reflist}}35{{reflist}}
38* [[Active pharmaceutical ingredient]]43* [[Active pharmaceutical ingredient]]
39* [[Analytical method validation]]44* [[Analytical method validation]]
+45* [[Solid-phase peptide synthesis]]
4046
41{{DEFAULTSORT:Patent expiry and biosimilars}}47{{DEFAULTSORT:Patent expiry and biosimilars}}