Limit of detection (revision 1)
Old revision·19:29, 13 Aug 2024·SigFigSindri
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| Limit of detection | |
|---|---|
| Abbreviation | LOD |
| Distinguished from | Limit of quantitation (LOQ) |
| Common convention | Signal-to-noise ratio of about 3:1 |
| Topic infobox · conventions | |
The limit of detection is the lowest concentration of an analyte that can be reliably distinguished from background, though not necessarily measured with acceptable precision. The limit of quantitation, at which a number can be reported, is higher — conventionally by a factor of about three.[1]
The distinction is practical rather than pedantic. Between the two limits an analyte is detectable but not measurable, and a determination reported in that region carries an uncertainty comparable with the value itself.[1]
References
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