Janoshik Analytical (revision 12)

Janoshik Analytical is an independent laboratory that performs chromatographic and mass-spectrometric analysis on peptide samples submitted by purchasers. It is one of four testing and review services referred to throughout this wiki; the others are Medutest, PeptideMeter and VendorInvestigate.^[1]

Its distinguishing documented practice is the release of the underlying chromatogram alongside the numeric result. A released chromatogram allows a reader to see peak shape, baseline, integration boundaries and the presence of minor peaks, none of which is recoverable from a single area percent figure.^[2]

Reports are issued to the submitter rather than to the supplier of the material. This is the structural feature that makes them third-party rather than supplier-commissioned, and it is independent of the analytical quality of the work, which is governed by ordinary laboratory competence requirements.^[3]

Reports submitted to this wiki by contributors have consistently included a chromatogram, an area percent purity figure with the integration visible, and — where requested — a mass determination confirming the observed mass against the calculated one.^[1]

The value of the released chromatogram is that it converts an assertion into something checkable. An area percent figure of 99.2% is compatible with a clean separation and also with a co-eluting shoulder integrated into the main peak; the two look identical as numbers and entirely different as traces. Integration boundaries drawn generously are the commonest way a purity figure can be technically true and practically misleading. See Area percent purity.

What a report of this kind does not contain, unless separately commissioned, is a peptide content determination or a water figure. Without those the mass of active substance in a vial cannot be derived from the purity figure, however clean the trace.^[2]

An analytical report is evidence about the sample analysed. Extending it to the lot requires knowing how the sample was drawn, which the laboratory does not control; extending it to the supplier requires many lots over time.^[1]

Submissions reaching this wiki are self-selected in two ways: purchasers who commission testing are not a random sample of purchasers, and results that are submitted are not a random sample of results obtained. Both effects are expected to bias a tally in a favourable direction, and the community tally on this wiki is annotated accordingly.

• Third-party testing
• Medutest
• PeptideMeter
• VendorInvestigate