Enteroendocrine L cell: difference between revisions
Diff·revision 4 → 5·18:53, 16 Jul 2024
Difference between revision 4 and revision 5 of Enteroendocrine L cell. 2 lines changed; the page grew by 321 bytes.
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| 6 | L cells are polarised epithelial cells with microvilli on the apical surface and secretory granules in the basolateral cytoplasm. The apical surface, open to the lumen, serves as the nutrient-sensing compartment; the basolateral surface contains receptors and ion channels that relay signals to the secretory machinery. L cells represent approximately 0.5–1% of all intestinal epithelial cells overall but are far more frequent in the ileum and colon than the duodenum.{{r|furness2013}} | 6 | L cells are polarised epithelial cells with microvilli on the apical surface and secretory granules in the basolateral cytoplasm. The apical surface, open to the lumen, serves as the nutrient-sensing compartment; the basolateral surface contains receptors and ion channels that relay signals to the secretory machinery. L cells represent approximately 0.5–1% of all intestinal epithelial cells overall but are far more frequent in the ileum and colon than the duodenum.{{r|furness2013}} |
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| + | 8 | L cells express nutrient-sensing receptors including receptors for free fatty acids (particularly for long-chain and short-chain fatty acids), a glucose transporter for apical glucose sensing, and taste receptors. This array of receptors allows L cells to respond to a broad spectrum of luminal contents.{{r|holst2007}} | |
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| 8 | == References == | 10 | == References == |
| 9 | {{reflist}} | 11 | {{reflist}} |