Custom peptide synthesis: difference between revisions
Diff·revision 4 → 5·07:53, 14 Nov 2024
Difference between revision 4 and revision 5 of Custom peptide synthesis. 3 lines changed; the page grew by 283 bytes.
| Revision 4 — 22:34, 1 Nov 2024 CategoryBot (talk) bot: normalise temperature formatting 2,407 bytes ±0 | Revision 5 — 07:53, 14 Nov 2024 MelanocortinMil (talk) add the collapse-temperature point, sourced 2,690 bytes +283 | ||
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| 10 | A custom order is defined by more than a sequence. Scale, purity grade, C-terminal functionality, any modifications such as acylation or cyclisation, salt form, and which determinations will appear on the [[Certificate of analysis|certificate]] are all specification items, and a quotation that does not enumerate them is quoting for an underdetermined thing.{{r|usp1503}} | 10 | A custom order is defined by more than a sequence. Scale, purity grade, C-terminal functionality, any modifications such as acylation or cyclisation, salt form, and which determinations will appear on the [[Certificate of analysis|certificate]] are all specification items, and a quotation that does not enumerate them is quoting for an underdetermined thing.{{r|usp1503}} |
| 11 | 11 | ||
| + | 12 | Price scales with length, with target purity, and with the difficulty of the sequence — which is not predictable from length alone. A quotation therefore reflects an assessment of synthetic difficulty as much as a price list.{{r|behrendt2016}} | |
| + | 13 | ||
| 12 | == What a specification should fix == | 14 | == What a specification should fix == |
| 13 | | Item | Why it matters | | 15 | | Item | Why it matters | |
| ⋮ | ⋮ | ||
| 32 | [[Category:Peptide synthesis]] | 34 | [[Category:Peptide synthesis]] |
| 33 | [[Category:Manufacturing and supply]] | 35 | [[Category:Manufacturing and supply]] |
| + | 36 | [[Category:Contract manufacturers]] | |
| 34 | 37 |