Custom peptide synthesis: difference between revisions
Diff·revision 10 → 11·06:41, 14 Mar 2025
Difference between revision 10 and revision 11 of Custom peptide synthesis. 3 lines changed; the page grew by 378 bytes.
| Revision 10 — 14:46, 15 Feb 2025 CouplingCillian (talk) add the crimp-seal step to the fill-and-finish description 3,399 bytes +150 | Revision 11 — 06:41, 14 Mar 2025 DiluentDiya (talk) close an unbalanced quotation mark 3,777 bytes +378 | ||
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| 32 | Declining to quote is also informative and is not a negative signal. Some sequences are genuinely difficult, some require capability a given house does not have, and a house that declines rather than accepting and failing is behaving reasonably. | 32 | Declining to quote is also informative and is not a negative signal. Some sequences are genuinely difficult, some require capability a given house does not have, and a house that declines rather than accepting and failing is behaving reasonably. |
| 33 | 33 | ||
| + | 34 | Quotations for sequences corresponding to compounds under patent, or to controlled substances, raise separate questions that are legal rather than technical. This wiki does not advise on them; see [[Regulatory status by jurisdiction]] and [[Patent expiry and biosimilars]].{{r|iso9001}} | |
| + | 35 | ||
| 34 | == References == | 36 | == References == |
| 35 | {{reflist}} | 37 | {{reflist}} |
| 36 | <ref name="behrendt2016">Behrendt R, White P, Offer J. "Advances in Fmoc solid-phase peptide synthesis." ''Journal of Peptide Science'' 22(1):4–27 (2016). PMID 26785684.</ref> | 38 | <ref name="behrendt2016">Behrendt R, White P, Offer J. "Advances in Fmoc solid-phase peptide synthesis." ''Journal of Peptide Science'' 22(1):4–27 (2016). PMID 26785684.</ref> |
| 37 | <ref name="usp1503">United States Pharmacopeia, General Chapter <1503>, ''Quality Attributes of Synthetic Peptide Drug Substances''.</ref> | 39 | <ref name="usp1503">United States Pharmacopeia, General Chapter <1503>, ''Quality Attributes of Synthetic Peptide Drug Substances''.</ref> |
| + | 40 | <ref name="iso9001">ISO 9001:2015, ''Quality management systems — Requirements''.</ref> | |
| 38 | 41 | ||
| 39 | == See also == | 42 | == See also == |