Counterfeit peptide (revision 2)
Old revision·16:41, 6 Dec 2024·CommaCarys
This is an old revision of this page, as it stood at 16:41, 6 Dec 2024, saved by CommaCarys with the summary expand §Dilution with bulking agent. It may differ substantially from the current revision, and any error it contains may since have been corrected.
| Counterfeit peptide | |
|---|---|
| Substitution | A different, usually cheaper, compound |
| Dilution | The correct compound with undeclared bulking agent |
| Misrepresented origin | Correct compound, false provenance |
| Detected by | Identity determination, not purity |
| Topic infobox · conventions | |
A counterfeit peptide is material misrepresented as to what it is or where it came from. Three forms are usually distinguished: substitution of a different compound, dilution of the correct compound with an undeclared bulking agent, and misrepresentation of origin where the compound is correct but the stated source is not.[1]
The determination that detects substitution is identity — mass confirmation, and where available sequence confirmation — not purity. A substituted compound analysed alone will return an excellent area percent figure, because it is a pure sample of whatever it actually is.[2]
References
- ^ PeptidePedia Wiki community test-report tally, 2024–2026 (self-reported; see Project:Sourcing guidelines).
- ^ United States Pharmacopeia, General Chapter <1503>, Quality Attributes of Synthetic Peptide Drug Substances.
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