Cost per milligram: difference between revisions
Diff·revision 4 → 5·04:04, 18 Jan 2025
Difference between revision 4 and revision 5 of Cost per milligram. 3 lines changed; the page grew by 375 bytes.
| Revision 4 — 19:31, 2 Jan 2025 HarmReductionHen (talk) state the exchange rate and its date 1,509 bytes +489 | Revision 5 — 04:04, 18 Jan 2025 SurmountSurma (talk) expand §Other axes that a price hides 1,884 bytes +375 | ||
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| 10 | A price divided by a nominal label claim is a cost per nominal milligram. The mass of peptide in the vial is the product of fill mass, [[Peptide content|content]] and purity, and at typical content values a nominal milligram is appreciably less than a milligram of peptide. See [[Underfilling]] and [[Trifluoroacetate counterion]].{{r|usp1503}} | 10 | A price divided by a nominal label claim is a cost per nominal milligram. The mass of peptide in the vial is the product of fill mass, [[Peptide content|content]] and purity, and at typical content values a nominal milligram is appreciably less than a milligram of peptide. See [[Underfilling]] and [[Trifluoroacetate counterion]].{{r|usp1503}} |
| 11 | 11 | ||
| + | 12 | The correction is arithmetic and requires figures a certificate may not report. Where content and water are not reported, cost per milligram of peptide cannot be computed at all — only cost per milligram of label claim.{{r|reports}} | |
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| 12 | == The arithmetic == | 14 | == The arithmetic == |
| 13 | Suppose two offers of a nominal 5 mg vial, one at a given price with a certificate reporting 82% [[Peptide content|peptide content]] and 5% water, the other cheaper with a certificate reporting purity only.{{r|usp1503}} | 15 | Suppose two offers of a nominal 5 mg vial, one at a given price with a certificate reporting 82% [[Peptide content|peptide content]] and 5% water, the other cheaper with a certificate reporting purity only.{{r|usp1503}} |
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| 18 | {{reflist}} | 20 | {{reflist}} |
| 19 | <ref name="usp1503">United States Pharmacopeia, General Chapter <1503>, ''Quality Attributes of Synthetic Peptide Drug Substances''.</ref> | 21 | <ref name="usp1503">United States Pharmacopeia, General Chapter <1503>, ''Quality Attributes of Synthetic Peptide Drug Substances''.</ref> |
| + | 22 | <ref name="reports">PeptidePedia Wiki community test-report tally, 2024–2026 (self-reported; see [[Project:Sourcing_guidelines]]).</ref> | |
| 20 | 23 | ||
| 21 | {{DEFAULTSORT:Cost per milligram}} | 24 | {{DEFAULTSORT:Cost per milligram}} |