Cold chain: difference between revisions
Diff·revision 21 → 22·18:09, 14 Sep 2024
Difference between revision 21 and revision 22 of Cold chain. 11 lines changed; the page grew by 835 bytes.
| Revision 21 — 13:05, 8 Sep 2024 PrepHPLC_Pia (talk) rv addition of price information per PP:VN 9,403 bytes +866 | Revision 22 — 18:09, 14 Sep 2024 StubSorterBot (talk) bot: repair redlinked category 10,238 bytes +835 | ||
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| 1 | {{Infobox concept | 1 | {{Infobox concept |
| 2 | | name = Cold chain | 2 | | name = Cold chain |
| + | 3 | | image = cold-chain.svg | |
| + | 4 | | caption = A cold chain is a series of custody transfers, each of which is a candidate point of failure and each of which is expected to leave a temperature record. | |
| 3 | | Scope = Manufacture, warehousing, freight, last mile, end use | 5 | | Scope = Manufacture, warehousing, freight, last mile, end use |
| 4 | | Principal controlled variable = Temperature | 6 | | Principal controlled variable = Temperature |
| ⋮ | ⋮ | ||
| 51 | ; Chemical threshold indicators : Change colour irreversibly when a threshold is crossed. Freeze indicators of this type are the standard means of detecting a freezing excursion in vaccine distribution. | 53 | ; Chemical threshold indicators : Change colour irreversibly when a threshold is crossed. Freeze indicators of this type are the standard means of detecting a freezing excursion in vaccine distribution. |
| 52 | ; Time–temperature integrating indicators : Accumulate a colour change as a function of both temperature and time, approximating the cumulative thermal exposure that matters for degradation. | 54 | ; Time–temperature integrating indicators : Accumulate a colour change as a function of both temperature and time, approximating the cumulative thermal exposure that matters for degradation. |
| + | 55 | ||
| + | 56 | |+ What each monitoring device can and cannot establish | |
| + | 57 | | !Device | Establishes | Cannot establish | | |
| + | 58 | |---|---|---| | |
| + | 59 | | Electronic data logger | Full time–temperature profile; permits mean kinetic temperature | Product temperature, unless placed in the payload | | |
| + | 60 | | Minimum–maximum thermometer | Extremes reached | Duration at any temperature | | |
| + | 61 | | Freeze indicator | That a freezing threshold was crossed | By how much, or for how long | | |
| + | 62 | | Time–temperature integrator | Cumulative exposure above a reference | The shape of the profile | | |
| + | 63 | | Vaccine vial monitor | Cumulative heat exposure at the individual vial | Freezing exposure | | |
| 53 | 64 | ||
| 54 | === Calibration and traceability === | 65 | === Calibration and traceability === |