Cold chain: difference between revisions
Diff·revision 17 → 18·12:57, 22 Aug 2024
Difference between revision 17 and revision 18 of Cold chain. 10 lines changed; the page grew by 778 bytes.
| Revision 17 — 00:06, 16 Aug 2024 SPPS_Sorrel (talk) rm unsourced claim per PP:V 6,832 bytes ±0 | Revision 18 — 12:57, 22 Aug 2024 MassSpecMarv (talk) clarify whether figure is gross or net mass 7,610 bytes +778 | ||
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| 5 | | Principal monitoring device = Electronic temperature data logger | 5 | | Principal monitoring device = Electronic temperature data logger |
| 6 | | Principal documented output = A continuous temperature record with custody points | 6 | | Principal documented output = A continuous temperature record with custody points |
| + | 7 | <!-- Storage definitions, USP <659> --> | |
| + | 8 | | Freezer = −25 to −10 °C | |
| + | 9 | | Cold = 2–8 °C | |
| + | 10 | | Cool = 8–15 °C | |
| + | 11 | | Controlled room temperature = 20–25 °C; mean kinetic temperature not above 25 °C | |
| + | 12 | | Warm = 30–40 °C | |
| 7 | }} | 13 | }} |
| 8 | 14 | ||
| ⋮ | ⋮ | ||
| 39 | 45 | ||
| 40 | Simpler devices remain in use and answer narrower questions: | 46 | Simpler devices remain in use and answer narrower questions: |
| + | 47 | ||
| + | 48 | ; Minimum–maximum thermometers : Record the extremes reached but not their duration, so they cannot support any cumulative calculation. | |
| + | 49 | ; Chemical threshold indicators : Change colour irreversibly when a threshold is crossed. Freeze indicators of this type are the standard means of detecting a freezing excursion in vaccine distribution. | |
| + | 50 | ; Time–temperature integrating indicators : Accumulate a colour change as a function of both temperature and time, approximating the cumulative thermal exposure that matters for degradation. | |
| 41 | 51 | ||
| 42 | == References == | 52 | == References == |