Cold-chain freight: difference between revisions
Diff·revision 14 → 15·22:43, 24 Jun 2025
Difference between revision 14 and revision 15 of Cold-chain freight. 6 lines changed; the page grew by 671 bytes.
| Revision 14 — 14:44, 3 Jun 2025 CustomsClarke (talk) correct the transit-time figure — the source gives a median, not a maximum 3,699 bytes ±0 | Revision 15 — 22:43, 24 Jun 2025 SupplyWatchSuri (talk) state the residual-moisture target with the method it is measured by 4,370 bytes +671 | ||
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| 34 | Reports submitted to this wiki that mention temperature control most often mention the state of the coolant on arrival. That is a weak observation: a pack can be solid on arrival after a period at ambient if it was frozen at dispatch, and can be liquid on arrival without the contents having exceeded the intended range.{{r|reports}} | 34 | Reports submitted to this wiki that mention temperature control most often mention the state of the coolant on arrival. That is a weak observation: a pack can be solid on arrival after a period at ambient if it was frozen at dispatch, and can be liquid on arrival without the contents having exceeded the intended range.{{r|reports}} |
| 35 | 35 | ||
| + | 36 | == How much it matters for a lyophilised peptide == | |
| + | 37 | Degradation rates in the dry solid are much lower than in solution. A lyophilised peptide is considerably more robust to a transit excursion than a reconstituted one, and short excursions at moderate temperature are unlikely to produce a measurable change.{{r|ich_q1a}} | |
| + | 38 | ||
| + | 39 | This is not a reason to disregard the cold chain, but it does bear on interpretation. An unfavourable [[Third-party testing|independent result]] on material shipped without temperature control is weak evidence about the supplier, because the material's history is unknown — the asymmetry described at [[Chain of custody]]. | |
| + | 40 | ||
| 36 | == References == | 41 | == References == |
| 37 | {{reflist}} | 42 | {{reflist}} |
| ⋮ | ⋮ | ||
| 45 | * [[Chain of custody]] | 50 | * [[Chain of custody]] |
| 46 | * [[Peptide stability table]] | 51 | * [[Peptide stability table]] |
| + | 52 | * [[Customs seizure]] | |
| 47 | 53 | ||
| 48 | {{DEFAULTSORT:Cold-chain freight}} | 54 | {{DEFAULTSORT:Cold-chain freight}} |