PeptidePedia The community reference

Chain of custody: difference between revisions

Diff·revision 11 → 12·05:46, 6 Jan 2025

Difference between revision 11 and revision 12 of Chain of custody. 6 lines changed; the page grew by 836 bytes.

Revision 11 — 11:51, 25 Dec 2024
SPPS_Sorrel (talk)
give the fields a compendially-complete certificate would carry
2,966 bytes ±0
Revision 12 — 05:46, 6 Jan 2025
EndotoxinEd (talk)
rm the ranking language; this wiki publishes no ranking
3,802 bytes +836
1{{Infobox method1{{Infobox method
2| name = Chain of custody2| name = Chain of custody
+3| subtitle = Sampling discipline
3| Records = Who held the sample, when, and under what conditions4| Records = Who held the sample, when, and under what conditions
4| Purpose = Excludes substitution, tampering and undocumented excursion5| Purpose = Excludes substitution, tampering and undocumented excursion
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19This is the single most common confound in community testing. A result reported as characterising a supplier's material may be characterising the purchaser's storage, and the two are indistinguishable without a custody record. See [[Temperature excursion]].20This is the single most common confound in community testing. A result reported as characterising a supplier's material may be characterising the purchaser's storage, and the two are indistinguishable without a custody record. See [[Temperature excursion]].
+21
+22== Why it is usually absent ==
+23The ordinary sequence for a community-submitted report is: material is bought; it is shipped by a carrier under unknown conditions; it is received and stored by the purchaser for some period; a vial is selected; it is posted to a laboratory. No step in that sequence is documented in a way that would satisfy a custody requirement.{{r|reports}}
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+25The consequences run in both directions and are not symmetric in the way people usually assume. Degradation in transit or storage produces a result worse than the material as shipped, so an unfavourable result from an uncontrolled chain is weak evidence against a supplier. A favourable result is less affected, since degradation does not improve purity — but it says nothing about whether that vial was representative.
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21== References ==27== References ==