Beta cell function: difference between revisions
Diff·revision 19 → 20·16:21, 22 Aug 2025
Difference between revision 19 and revision 20 of Beta cell function. 2 lines changed; the page grew by 345 bytes.
| Revision 19 — 01:26, 27 Jul 2025 CategoryBot (talk) bot: update parent category chain 5,751 bytes ±0 | Revision 20 — 16:21, 22 Aug 2025 Chromatokid (talk) add a figure for the secretion time course and caption it 6,096 bytes +345 | ||
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| 39 | Substantial weight loss by any means improves the disposition index, and remission studies following large sustained weight loss have reported recovery of first-phase secretion in a subset of participants — most often those with shorter diabetes duration. This is the strongest available evidence that some of the functional loss in type 2 diabetes is reversible.{{r|bergman2002}} | 39 | Substantial weight loss by any means improves the disposition index, and remission studies following large sustained weight loss have reported recovery of first-phase secretion in a subset of participants — most often those with shorter diabetes duration. This is the strongest available evidence that some of the functional loss in type 2 diabetes is reversible.{{r|bergman2002}} |
| 40 | 40 | ||
| + | 41 | Neither observation supports a claim that any particular drug or regimen "restores" or "heals" beta cells. That framing appears frequently in promotional material and is not supported by the trial literature; the measured changes are improvements in an index under continuing treatment or after weight loss, not demonstrations of regeneration. | |
| + | 42 | ||
| 41 | == References == | 43 | == References == |
| 42 | {{reflist}} | 44 | {{reflist}} |