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Baseline laboratory panel: difference between revisions

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Revision 13 — 01:54, 30 Mar 2025
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split the analytical performance from the clinical interpretation
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Revision 14 — 14:58, 17 Apr 2025
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32Reference intervals are laboratory-specific, derived from that laboratory's own population and assay. A value described as "out of range" is out of that laboratory's range, and a value from another laboratory may sit differently against its own.{{r|wallace2004}}32Reference intervals are laboratory-specific, derived from that laboratory's own population and assay. A value described as "out of range" is out of that laboratory's range, and a value from another laboratory may sit differently against its own.{{r|wallace2004}}
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+34Regression to the mean operates on any value selected for being extreme. A repeat measurement after an abnormal one tends to be closer to the mean whether or not anything was done in between — which is why a single abnormal value is weaker evidence than a trend.{{r|hrobjartsson2010}}
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34== References ==36== References ==
35{{reflist}}37{{reflist}}
36<ref name="ada2024">American Diabetes Association. "Standards of Care in Diabetes." ''Diabetes Care'' 47(Suppl 1) (2024).</ref>38<ref name="ada2024">American Diabetes Association. "Standards of Care in Diabetes." ''Diabetes Care'' 47(Suppl 1) (2024).</ref>
37<ref name="wallace2004">Wallace TM, Levy JC, Matthews DR. "Use and abuse of HOMA modeling." ''Diabetes Care'' 27(6):1487–1495 (2004). PMID 15161807.</ref>39<ref name="wallace2004">Wallace TM, Levy JC, Matthews DR. "Use and abuse of HOMA modeling." ''Diabetes Care'' 27(6):1487–1495 (2004). PMID 15161807.</ref>
+40<ref name="hrobjartsson2010">Hróbjartsson A, Gøtzsche PC. "Placebo interventions for all clinical conditions." ''Cochrane Database of Systematic Reviews'' (1):CD003974 (2010). PMID 20091554.</ref>
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39== See also ==42== See also ==