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Adverse effects of GLP-1 receptor agonists: difference between revisions

Diff·revision 16 → 17·18:44, 1 Jan 2025

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Revision 16 — 21:03, 16 Dec 2024
GastroparesisGwen (talk)
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Revision 17 — 18:44, 1 Jan 2025
SarcopeniaSefa (talk)
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32Acute pancreatitis has been reported and is uncommon. Trial data have not established a causal relationship, and the background rate in populations with obesity and type 2 diabetes is itself elevated, which makes a modest excess hard to detect.{{r|nauck2016}}32Acute pancreatitis has been reported and is uncommon. Trial data have not established a causal relationship, and the background rate in populations with obesity and type 2 diabetes is itself elevated, which makes a modest excess hard to detect.{{r|nauck2016}}
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+34The medullary thyroid carcinoma contraindication derives from rodent C-cell hyperplasia and tumours at high exposure. Rodent C cells express the receptor at much higher density than human C cells, and no human signal has been established; the contraindication is precautionary. See [[Medullary thyroid carcinoma]].{{r|drucker2018}}
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34== References ==36== References ==
35{{reflist}}37{{reflist}}
44* [[Gastric emptying]]46* [[Gastric emptying]]
45* [[Aspiration risk under anaesthesia]]47* [[Aspiration risk under anaesthesia]]
+48* [[Hypoglycaemia]]
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47{{DEFAULTSORT:Adverse effects of GLP-1 receptor agonists}}50{{DEFAULTSORT:Adverse effects of GLP-1 receptor agonists}}